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Introduction: Recurrent urinary tract infections (UTIs) are a significant clinical issue, especially in women, with Escherichia coli (E. coli) being the most common pathogen. The frequent use of antibiotics for treatment has raised concerns about antibiotic resistance, driving the need for alternative therapies. Homeopathy, a holistic and individualized approach, offers potential solutions for managing recurrent UTIs by focusing on the body's natural healing processes. Methods: This review explores the role of E. coli in recurrent UTIs and evaluates the effectiveness of homeopathic remedies such as Cantharis, Staphysagria, and Apis mellifica. We systematically examined clinical studies, case reports, and other relevant literature to assess homeopathy’s role as an adjunct or alternative to conventional antibiotic treatments in the management of recurrent UTIs. Results:The review found that homeopathic treatments were often effective in reducing the frequency of recurrent UTIs, especially when used alongside or in place of antibiotics. Remedies like Cantharis helped alleviate burning sensations, Apis mellifica reduced inflammation, and Staphysagria was useful for UTIs associated with emotional stress. Although E. coli eradication was not always directly reported, symptom relief and recurrence prevention were notable outcomes. Discussion: While more extensive clinical trials are necessary, current evidence supports homeopathy as a beneficial, personalized treatment option for recurrent UTIs caused by E. coli. This individualized care approach, focused on the patient’s constitution, presents a promising alternative to conventional treatments. Conclusion: In conclusion, homeopathic remedies, when tailored to the individual, offer a promising complementary or alternative treatment for recurrent UTIs caused by E. coli. While more research is required to solidify the clinical benefits, homeopathy’s potential to reduce antibiotic reliance and prevent recurrence suggests it could play a vital role in managing recurrent UTIs in a more holistic manner.

Keywords: Antibiotic resistance, Apis mellifica, Cantharis, E. coli, Homeopathy, Recurrent Urinary Tract Infection, Staphysagria.