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Background: Diabetic foot ulcers (DFUs) are a major complication of diabetes, often resulting in high morbidity and potential amputations if not treated properly. Conventional treatments, such as antibiotics, debridement, and advanced wound dressings, have limitations related to wound healing, recurrence, and infection control.

Objective: This review aims to evaluate the efficacy of Ayurvedic formulations, specifically Aragvadhadi Gana (oral) and Aragvadhadi Ghrut (topical), in the management of DFUs. It compares the outcomes of these Ayurvedic treatments with conventional therapies and highlights their potential advantages in wound healing.

Methods: A comprehensive review of clinical trials and observational studies was conducted. Data on the therapeutic properties of Aragvadhadi Gana and Aragvadhadi Ghrut, such as antimicrobial, anti-inflammatory, and tissue-regenerative effects, were analyzed. The healing rates, infection control, and recurrence prevention in DFUs treated with these Ayurvedic formulations were compared to conventional treatment methods.

Results: The reviewed studies indicate that Aragvadhadi Gana and Aragvadhadi Ghrut significantly improved wound healing rates and reduced complications such as infections and recurrences in DFUs. These formulations demonstrated comparable or superior outcomes in some cases compared to conventional treatments, especially in promoting tissue regeneration and controlling infection.

Conclusion: Aragvadhadi Gana and Aragvadhadi Ghrut show promise as effective Ayurvedic alternatives or complementary therapies in DFU management. However, more extensive clinical trials are necessary to confirm their long-term efficacy and establish their role in modern wound care strategies, particularly where conventional treatments are less effective or inaccessible.