PHARMACOGNOSTICAL AND PHARMACEUTICAL ANALYSIS OF KANTKATERYADI VATI–AN AYURVEDIC POLYHERBAL FORMULATION FOR CLINICAL TRIAL OF TYPE 2 DIABETES MELLITUS
Aim: To analyze the Pharmacognostical and Pharmaceutical properties of Kantkateryadi Vati
Materials and Methods: Kantkateryadi Vati was subjected to microscopic evaluation for pharmacognostical study, physico-chemical analysis like hardness, weight variation, loss on drying, ash value, acid insoluble extract, pH value, water soluble extract, alcohol soluble extract and high performance thin layer chromatography (HPTLC).
Result: Pharmacognostical study showed the presence of certain identifying characteristics of all the ingredients of Kantkateryadi Vati that is Kantkateri, Madhuka, Amalaki, Haritaki, Bibhitaka, Chitraka . In pharmaceutical study, preliminary physico-chemical analysis showed that hardness of 6.8 Kg/cm2, ash value 13.82%w/w, loss on drying 13.12% w/w, water soluble extract 20.85% w/w, alcohol soluble extract 31.40% w/w and pH value 6.5. HPTLC analysis showed at 254nm 11 peaks and at 366 nm 7 peaks.
Conclusion-Present work was carried out to standardize the polyherbal formulation of Kantkateryadi Vati in terms of its identity, quality and purity. Pharmacognostical and physico-chemical observations revealed the specific characters of all the active constituents in the preparation.
Keywords: Type 2 Diabeties Mellitus, pharmaceutics, pharmacognosy, Kantkateryadi Vati