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High serum cholesterol levels leading to aterosclerosis can cause coronary heart disease (CHD).Hyperlipidemia is a main risk element for the expansion of coronary heart disease and is the most usual source of mortality and morbidity worldwide. presently available synthetic drug of hyperlipidemia are associated with a number of side effects. In recent times, a large volume of work aimed at the efficacy of herbal products, as they are safe and effective alternatives to synthetic drugs.The aim of the present study is to explore the phytochemical profile and anti-hyperlipidemic activity of entire plant of hydroalcoholic extract Dactylorhiza incarnata high-fat diet induced hyperlipidemic rats ata dose of 100 and 200mg/kg. Qualitative analysis of various phytochemical ingredient and quantitative analysis of total phenolic and flavonoids were determined by the well-known test agreement available in the text. The activity was evaluate by assessment of serum lipid profile viz. total cholesterol (TC), triglycerides (TG) and high density lipoprotein cholesterol of control and drug-treated animals. Phytochemical analysis revealed the appearance of phenols, proteins and amino acids, carbohydrates, saponins and diterpenes. The extract exhibited a dose dependent anti-hyperlipidemic activity and at dose level 200 mg/kg p.o. the extract indicated a significant decrease in the levels of serum TC, TG and HDL-C. The present study exhibit that the extract exhibits a potent lipid lowering activity in diet induced hyperlipidemia which account for some of the medical claims attributed to this plant.