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In Ayurveda, Bhagandara described by Aacharya Sushruta can be categorized under Dusta vrana i e. noncollapsable, unhealthy infected wound with persistent drainage of pus. Bhagandara can be compared to Fistula-in-ano in modern science on the basis of similarities in the symptomatology mentioned in Ayurvedic and Modern text books. According to modern science fistula in ano is one of the most common ano-rectal diseases in which the chronic granulating track run from the anal canal or rectum to the peri-anal skin or perineum and is associated with considerable discomfort and morbidity to the patient.