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De- Quervain’s is the a stenosing tenosynovitis of the first dorsal compartment of the wrist affecting abductor pollicis longus (APL) and the extensor pollicis brevis (EPB ) tendons that control the movement of the thumb. Intensity of pain in may be exacerbated by grasping, thumb abduction, and ulnar deviation of the wrist. Repetitive typing, lifting, and manipulation around wrist region are considered as risk factors.

In Ayurveda; De-Quervain’s tenosynovitis can be correlated with Snayu-Vikara (Snayugata vata); including the symptoms such as sula, stambha, kampa, akṣhepa, ayama kubjatva, and khalli etc. mentioned by various Acharyas. Acharya Susruta and Vagbhaṭa has described specific treatment for the Snayugatavata i.e. Snehana, Upanaha, Agnikarma,  Bandhana and Unmardana.  Considering this, a clinical trial was planned to evaluate the efficacy of Agnikarma along with Aabha guggulu in the management of snayu vikara.

This clinical study was registered with CTRI/2019/03/017944 and the study was started after approval from institutional ethics committee with reference number IEC/ACA/2017/67.  In this study, total 30 patients were selected and randomly divided in to 3 groups. Group A (n=10) was planned with Agni karma procedure; Group B (n=10) was planned with orally intake of Aabha Guggulu (500mg) twice a day with Luke warm water. Group C (n=10) was planned with combination of Aabha guggulu and Agni karma procedure. In all groups, treatment duration was 3 weeks and follow- up to 12 weeks.  

Result was assessed on various subjective such as pain and objective parameters such as Finkelstein test, tenderness and Range of Motion (ROM). Overall relief in symptoms was found such as 67.53% in Group A, 23.01% in Group B and 73.93% in Group C.  It concludes that Agni karma along with Aabha Guggulu is more effective in the management of Snayu-Vikara.